Risks and benefits of hormone replacement therapy: the evidence speaks.

نویسندگان

  • Karin H Humphries
  • Sabrina Gill
چکیده

Until recently, observational studies suggested a decreased risk of cardiovascular disease, osteoporotic fractures, cognitive decline and colon cancer with the use of hormone replacement therapy (HRT). Recent randomized controlled trials have failed to show a protective effect of HRT in reducing the risk of coronary artery disease and instead have revealed an increased risk of heart disease, stroke, invasive breast cancer and venous thromboembolism, but a decreased risk of colorectal cancer and osteoporotic fractures. In this article we review the current evidence of the risks and benefits of HRT.

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عنوان ژورنال:
  • CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

دوره 168 8  شماره 

صفحات  -

تاریخ انتشار 2003